League of Legends Seraphine players may find her to be a difficult champ to build out properly. You'll notice that her build varies when she is playing against either diversified or homogenous team comps, showing you should not follow the same Seraphine build every single round of League of Legends
The most critical items to include in your champ's build include: Echoes of Helia, Rylai's Crystal Scepter, and Ardent Censer. Players who added these items in their kits had a better winrate than those who utilized other Seraphine builds. Moreover, if you are battling a mixed enemy team arrangement, you should strongly consider getting yourself the Sorcery, and Inspiration runes. In recent matches, she won the largest fraction of her games when built with these runes.
We came up with our Seraphine build suggestions by examining 91,837 recently ranked LoL matches with her selected. We only propose the best winrate Seraphine builds that have been built by ranked LoL players enough times for us to suggest them. With so many matches in our dataset, we are very confident in our suggested builds.