Items that counter Health stacking, such as Liandry's Torment and Blade of the Ruined King, are very effective against Vladimir.
Making Vladimir use Sanguine Pool at the start of a fight will maximize the Health cost of the ability to him.
Try to take Vladimir down before Hemoplague detonates, as it will heal him for each afflicted enemy Champion.
The stats provided here underscore several influential Seraphine vs. Vladimir counter stats that may help you figure out the distinctions between this pair of champs. For instance, Seraphine’s KDA ratio ([kills + assists] / deaths) of NaN is more than Vladimir’s ratio of NaN, highlighting that Seraphine may be more central to her team's team fighting capacity than Vladimir. This observation is in large part fueled by the differences in assists.
Seraphine typically has a slightly smaller longest killing spree than her counter does. Commonly, she receives less damage than Vladimir. This is usually reflective of differing health capacities, but it can also indicate that the champion with more HP has less mobility and thus is unable to kite away from further damage when engaged or poked.
Both LoL champions are great. Both have their strengths, weaknesses, and counters. In League's current meta, Seraphine usually wins when trying to fight Vladimir, with a 51.9% win rate. Therefore, Seraphine makes a good counter for Vladimir.
While Seraphine does have a higher winrate compared to Vladimir, when they face off with one another, Seraphine also has a much lower difficulty level that makes her a less difficult champ to learn and master. You still need to be cautious when picking Seraphine into Vladimir.
Additionally, Seraphine has a lot of CC and other utility, a similar amount to Vladimir. This often makes her just as valuable during team fights, especially when fighting champions with a ton of burst damage.
While there is not a single best champion for every situation in League of Legends, in Seraphine vs Vladimir matchups, Seraphine is the better champion with a higher win rate, less champion complexity, and a similar amount of utility to help out your teammates during teamfights.
Seraphine is a decent counter for Vladimir. Focus your actions on increasing your gold income and destroying objectives. If you do that, you should do very well as Seraphine against Vladimir.
To truly master Seraphine to counter Vladimir during both the laning and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and stats displayed here, you will grow your win rate significantly and be closer to League of Legends pro players.
Seraphine on average gets less CS compared to Vladimir. Champs who on average don't take many minion kills usualy don't have to have much CS to be valuable teammates, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually need several high cost items to be effective. In either situation, try to exceed the numbers shown here to do well.
The most important items to use in your Seraphine versus Vladimir build include Seraph's Embrace, Dream Maker, and Staff of Flowing Water. When Seraphine incorporated at least these three items in her build, she performed a lot better countering Vladimir than with most other typical counter builds. In fact, Seraphine had an average win rate of 51.9% when countering Vladimir with these items in her kit.
To have the best probability of annihilating Vladimir as Seraphine, Seraphine players should equip the Summon Aery, Manaflow Band, Transcendence, Gathering Storm, Triple Tonic, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune sets players chose for Seraphine vs Vladimir clashes, this mixture of runes yielded the highest win rate. In fact, these runes provided a 51.9% win rate overall.
By default, tips, stats, and builds on how to beat Vladimir as Seraphine are presented for all ranked divisions combined. To scope the statistics and builds to a specific rank, you can use the selection menu located earlier in the counter matchup guide.