Zilean is fragile if a team focuses on him, but otherwise he's very difficult to kill. Commit to killing him as a team.
If you're able to match Zilean's speed, it can sometimes be beneficial to wait until his ultimate has faded before landing the killing blow.
The stat comparisons provided here emphasize some strategic Seraphine versus Zilean matchup statistics that may help you grasp the differences between the two. Seraphine’s KDA ratio ([kills + assists] / deaths) of NaN is better than Zilean’s ratio of NaN, demonstrating that Seraphine may be more central to her team's team fighting effectiveness than Zilean..
Seraphine normally has a similar longest kill spree as her foe does. Typically, she takes a similar amount of damage to Zilean. This commonly reflects differing health capacities, yet it can also illustrate that the champ with increased health has less mobility and thus is unable to kite away from additional damage when poked or engaged.
Both League of Legends champs are great champions. Both champs have their pros and cons. In the game's current meta, Seraphine usually loses when taking on Zilean, with a 47.6% win rate. Thus, Seraphine makes a poor counter to Zilean.
While Seraphine does have a lower winrate compared to Zilean, when on opposite teams, Seraphine also has a much lower level of difficulty that makes her a less difficult champ to pick up and master. You should expect to face a difficult match when picking Seraphine into Zilean.
Additionally, Seraphine has a very large amount of utility and CC, a similar amount to Zilean. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion overall in League of Legends, in Seraphine vs Zilean matchups, Zilean is the better champ with a lower win rate, less champion complexity, and a similar amount of utility to help out your allied champions during team fights.
Seraphine is a terribly counter for Zilean. Focus your tactics on keeping up your CS and destroying objectives. If you can do that, you should do very well as Seraphine against Zilean.
To learn all of the intricacies of Seraphine in order to counter Zilean during both the laning and mid / late game phases of League of Legends, you should keep reading to gather a few extra tricks and insights into this matchup. If you mind the build and suggestions presented above, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Seraphine usually racks up more CS relative to Zilean. Champs who typically don't get much CS usualy don't need much CS to be valuable teammates, such as sup champs. These kinds of champions are capable of scaling properly off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically need several high cost items to be effective. In either case, try to surpass the values reported here to do well.
The most important items to have in your Seraphine versus Zilean build consist of Celestial Opposition, Staff of Flowing Water, and Moonstone Renewer. When Seraphine combined at least these three pieces in her build, she performed significantly better when fighting Zilean than with many other commonly used builds. In fact, Seraphine boasted an average win rate of 47.6% when countering Zilean with these items in her kit.
To have the highest chance of crushing Zilean as Seraphine, Seraphine players should take the Summon Aery, Manaflow Band, Transcendence, Gathering Storm, Triple Tonic, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the runes that we analyzed for Seraphine vs Zilean counterpicks, this mix of runes yielded the best win rate. In fact, these runes provided a 47.6% winrate overall.
If you would like to get Seraphine versus Zilean tips and matchup stats and build suggestions for a an individual rank, feel free to select one from the selection menu provided above. By default, the stats and guides displayed are computed using every round played with both champs.