Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The stats shown on this page clarify several important Vayne versus Seraphine counter stats that can help us interpret the differences between these two champs. As an example, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is better than Seraphine’s ratio of NaN, showing that Vayne may be more central to her team's team fighting capacity than Seraphine. This observation is largely fueled by the difference in kills.
Vayne normally has a much larger longest killing spree than her matchup does. Typically, she receives more damage than Seraphine. This commonly reflects different amounts of tankyness; however, it can also illustrate that the one champion has less agility and thus is unable to kite away from further damage when engaged or poked.
Both LoL champions are great champions. Both champs have their pros and cons. In League's current meta, Vayne usually fairs equally well when facing off against Seraphine, with a 50.7% win rate. Thus, Vayne makes an ok counter for Seraphine.
While Vayne does have a higher win rate than Seraphine, when they face off with one another, Vayne also has a much greater difficulty level that makes her a more complex champion to learn and master. You still need to be cautious when picking Vayne into Seraphineas her relative depth means that you may not be able to reach her full potential without a lot of practice beforehand.
Moreover, Vayne has some amount of CC and other utility, a similar amount to Seraphine. This often makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there isn't one best champion for every situation in League of Legends, in Vayne vs Seraphine matchups, Vayne is the better champion with a similar win rate, more champion depth, and a similar amount of utility to help out your team members during team fights.
Vayne is a decent counter for Seraphine. You will do well by focussing your strategy on increasing your CS and taking out objectives. If you are able to do that, you should hold your own as Vayne against Seraphine.
If you would like to learn all of the intricacies of Vayne to counter Seraphine during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra tips and tricks for this matchup. If you mind the build and suggestions shown above, you should grow your win rate by a lot and be that much closer to League of Legends pro players.
Vayne most often picks up more CS relative to Seraphine. Champions who on average don't take much CS often don't have to have much CS to be effective, such as sup champs. They are able to scale properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically require several high cost items to be effective. In either case, try to surpass the values reported here to do well.
The most important items to have in your Vayne versus Seraphine build include Mercurial Scimitar, Blade of The Ruined King, and Terminus. When Vayne used at least these three items in her build, she performed significantly better when facing Seraphine than with many other commonly used item sets. In fact, Vayne had an average winrate of 50.7% when countering Seraphine with this build.
To have the highest likelihood of annihilating Seraphine as Vayne, Vayne players should equip the Fleet Footwork, Triumph, Legend: Alacrity, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Out of all the runes we have analyed for Vayne vs Seraphine counters, this order of runes resulted in the best win rate. Notably, these runes provided a 50.7% winrate overall.
If you want to see Vayne versus Seraphine tips and counter stats for a a particular skill level, please choose one from the selection menu shown above. By default, the statistics and strategies shown are calculated using all games finished with both champions.