Use Arcane Shift to help line up your other skill shots.
You can line up Trueshot Barrage to hit multiple minion waves or even Monsters.
You can play Ezreal either as a Attack Damage carry or Ability Power carry depending on how you build him.
Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
The Ezreal Kai'Sa synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kai'Sa, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ezreal sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Kai'Sa. His KDA went down from NaN to NaN. This decrease shows that Kai'Sa helps Ezreal perform not as well in ranked League matches. Yet, the small difference indicates that this performance change is not very impactful.
When Ezreal tries to synergize with Kai'Sa, he observes a small decrease in his full damage dealt. This difference may indicate that Kai'Sa doesn't help cover for him to dish out more damage or that her allyship also helps increase the round's duration. Similarly, when Ezreal is played with Kai'Sa on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Kai'Sa.
Moreover, when Ezreal plays with Kai'Sa on the same side, he typically takes a little more damage than when he fights alone. Getting dealt more damage may mean that Kai'Sa does a poor job of protecting Ezreal in team fights.
There is no one best champion pairing for Ezreal that will always be his ideal teammate. Yet, overall, Kai'Sa is a terrible teammate for Ezreal. By locking into the same team as Ezreal, she lowers their win rate by -6.3% to 40.6%. This proves that there is a very bad bond between Ezreal and Kai'Sa that results in them performing not as well together than alone.
Kai'Sa has a lower difficulty than Ezreal. That means you don't need to be very careful when finding Kai'Sa teammates to go into battle on the same side as, as they will need a lower level of skill to do well with you.
When playing together, you will likely observe an overall large increase in your team’s ability to dish out massive AD. Combined, these champs should be able to take down targets with auto-attacks and other AD damage abilities.
Although, by aligning Ezreal and Kai'Sa together, you will not be giving your other allies a great deal of crowd control. Make sure to have other champs on your team that offsets this disparity in their capabilities.
Regardless of the skill of your Kai'Sa ally, you should focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you should do well, regardless.
If you would like to learn all of the intricacies of Ezreal in order to work well with Kai'Sa during both the lane and mid / late game phases of League of Legends rounds, you should keep reading to learn a few extra tips and tricks for this champion pairing. If you mind the build and suggestions presented above, you will grow your win rate by a lot.
The ideal items to have in your Ezreal and Kai'Sa synergy build include Muramana, Essence Reaver, and Navori Quickblades. When Ezreal used at least these three finished items in his build, he performed a lot better as an ally of Kai'Sa than with many other commonly used builds. In fact, Ezreal had an average winrate of 40.6% helping carry Kai'Sa with these items in his kit.
To have the greatest likelihood of defeating your oponents, you should equip the Press the Attack, Presence of Mind, Legend: Bloodline, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Of all the runes players chose for Ezreal and Kai'Sa pairings, this blending of runes resulted in the best win rate. In fact, these runes gave a 40.6% win rate overall.
By default, tips, stats, and builds on how to team up Kai'Sa with Ezreal are given for all ranked divisions combined. If you want to narrow the stats and builds to a particular rank, you may use the selection menu located earlier in the counter matchup guide.