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How to Synergize Karthus with Annie on the Same TeamKarthus is in the b tier of champions

Karthus with Annie

How to Win With Karthus and Annie Paired TogetherKarthus is in the a tier of champions
Mage
Mage

How to Synergize Karthus and Annie

based on 584 Karthus with Annie pairs
Win Rate
48.1 %
K/D/A
2.24
Pick Rate
1.2 %

How We Analyze Champion Pairings in LoL

At MOBA Champion, we download the results of from millions of League of Legends rounds directly from Riot Games each and every week. Karthus has been on the same team as Annie in 584 recent, ranked matches. By accumulating so much complete data directly from the developers of League, we are totally sure that we can present to you high-quality, accurate builds to help Karthus play with Annie. It is very rare for Karthus to play with Annie as allies. This pairing has only taken place in approx. 1.2% of games with Karthus.

Karthus Annie Synergy Summary

Unfortunately, Karthus has done a dismal job of fighting on the same side as Annie. Usually, he wins a poor 48.1% of matches the champs appear on the same team. If you want to play better as Karthus when fighting on the same team as Annie by figuring out how to better synergize your tactics with her, then dig into the full build (with items, runes, summoner spells, and skills) below!

Best Karthus vs Annie Counter Build

Items

Starter Items

Time Target
Scorchclaw PupHealth Potion

Early Items

~5 Mins
BootsAmplifying Tome

Core Karthus Items

~22 Mins
MalignanceStormsurgeLiandry's Torment

Optional Items

Rabadon's DeathcapVoid StaffShadowflame

Summoner Spells

summonerexhaust summoner spell D
summonersmite summoner spell F

Skill Order

First skill for Karthus to level upq
>
Second ability for Karthus to level upe
>
Last skill for Karthus to max outw

Runes

InspirationFirst StrikeMagical FootwearFuture's MarketCosmic Insight
DominationEyeball CollectionUltimate Hunter
Adaptive ForceAdaptive ForceArmor
Karthus's passive ability p
Karthus's q ability q
Karthus's w ability w
Karthus's e ability e
Karthus's ultimate ability r
1
Q
2
E
3
Q
4
W
5
Q
6
R
7
Q
8
E
9
Q
10
E
11
R
12
E
13
E
14
W
15
W
16
R

Guide to Synergizing Karthus and Annie

Tips for Playing as Karthus with Annie

Lay Waste is very strong at farming minions and harassing enemy champions.

Ask your allies to help point out when you should use Requiem to get kills in different lanes.

Advice to Understand How Annie Will Play

Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.

Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.

Storing a stun for use with her ultimate can turn the tide of a team fight.

Karthus Annie Synergy Stats

Karthus Image
Win Rate
48.1 %
VS
Win Rate
51.9 %
Annie Image
7
< Kills >
7
7.6
< Deaths >
7.6
10
< Assists >
9.5
1.67
< Killing Sprees >
1.63
74
< Minions Killed >
88
1
< Dragons Killed >
0.89
0.28
< Inhibitors >
0.28
254
< Physical Damage >
246
28,376
< Magic Damage >
29,153
2,145
< True Damage >
2,031
30,775
< Damage Dealt >
31,430
30,936
< Damage Taken >
29,785
12,918
< Gold Earned >
12,799
1.07
< Towers >
1.08
0.32
< Baron Takedowns >
0.23
10,395
< Total Healing >
9,279
15,070
< Experience >
14,921
19
< Vision Score >
19
7
< Wards Placed >
7
236
< Time Dealing CC >
221

How to Play with Annie as Karthus in LoL

The Karthus Annie synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Annie, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.

Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Annie. His KDA fell from NaN to NaN. This decrease shows that Annie helps Karthus perform worse in competitive League of Legends matches. Yet, the small difference demonstrates that this performance change is only marginal.

When Karthus is paired with Annie, he sees a barely noticable drop in his full damage dealt. This change could indicate that Annie does not help protection for him to dish out more damage or that her support also helps extend the match's duration. Similarly, when Karthus is played with Annie on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing alongside Annie.

Moreover, when Karthus plays with Annie on the same side, he often takes a little more damage than when he plays alone. Taking more damage may indicate that Annie does a poor job of protecting Karthus during teamfights.

Synergies between Karthus and Annie

Damage Types Compared

Karthus
Annie
Physical Damage
Magic Damage
True Damage

Champion Playstyles Contrasted

Karthus
Annie

Is Karthus better when played alongside Annie?

There is no perfect ally for Karthus that will always be his best ally. Yet, overall, Annie is a very typical ally for Karthus. By playing on the same team as Karthus, she raises their win rate by 0.8% to 48.1%. This demonstrates that there is not really a strong synergy between Karthus and Annie that results in them performing at the top of their game together than without each other.

Annie has a lower difficulty than Karthus. That means Karthus players don't need to be careful when arranging Annie comrades to go into battle on the same side as, as they will need a relatively low level of skill to work well with you.

Fighting on the same side, Karthus players should see an overall large increase in your team’s capability to deal magical damage. When paired, these two can deal quite a lot of AP type damage.

Although, by bringing Karthus and Annie together, you may not be providing your other teammates a lot of AD. We recommend you include other champions on your team that nullifies this relative hole in this pairing's kit.

Regardless of your Annie ally's skill level, you need to focus on increasing your income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you will do well anyway.

Additional Information for Karthus Players

How We Calculated Our Karthus Annie Synergy Build and Stats

For this guide on pairing Karthus and Annie, we analyzed 584 ranked and recent League of Legends matches. We perform advanced data cleaning and statistical methods to guarantee that our team synergy stats are accurate and reliable. You can be confident that our recommended build to pair Karthus with Annie comes from actual data and is not the fabrication of some random LoL player, as some other sites provide. You can use the filters at the top of the page to view your division's most relevant stats and build.

Other Useful Resources

Further Insights to Win with this Champion Pairing

If you would like to truly master Karthus in order to work well with Annie during both the early game and mid / late game phases of League of Legends games, you should continue reading to learn additional tricks and insights into this champion pairing. If you use the build and suggestions shown here, you should increase your win rate by a lot.

The most important finished items to get in your Karthus and Annie synergy build consist of Malignance, Stormsurge, and Liandry's Torment. When Karthus bought at least these three great items in his build, he performed significantly better when paired up with Annie than with most other typical builds. In fact, Karthus boasted an average winrate of 48.1% when playing alongside Annie with this build.

To have the best chance of vanquishing your oponents, you should use the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune builds players chose for Karthus and Annie pairings, this mix of runes yielded the top win rate. Notably, these runes provided a 48.1% winrate overall.

If you want to get Karthus with Annie synergy tips and builds for a an individual division rank, please select one from the selection menu provided above. At first, the stats and strategies shown are calculated using all games with data with these champs.