To maximize your ultimate's damage use it when there are many spheres on the battlefield.
After you hit an enemy champion with Force of Will follow up with Dark Sphere, they'll be slowed and have a hard time avoiding it.
Get one of your spells to rank 5 as quickly as possible, they gain powerful bonus effects at max rank.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Syndra Cassiopeia synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Cassiopeia, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Syndra sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Cassiopeia. His KDA fell from NaN to NaN. This worsening shows that Cassiopeia helps Syndra perform poorer in ranked League of Legends games. Yet, the small difference indicates that this performance change is only marginal.
When Syndra is an ally to Cassiopeia, she sees a noticable drop in her complete damage output. This could demonstrate that Cassiopeia does not support by providing protection for her to deal more damage or that her support also helps increase the game's duration. Similarly, when Syndra is played together with Cassiopeia on the same side, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing alongside Cassiopeia.
Additionally, when Syndra plays with Cassiopeia on the same side, she on average receives a little less damage than when she fights alone. Taking not as much damage could mean that Cassiopeia does a decent job of protecting Syndra during teamfights.
There is no universally accepted best companion for Syndra that will no matter what be her top ally. Yet, Cassiopeia is a very bad teammate for Syndra. By playing on the same team as Syndra, she lowers their win rate by -4.0% to 44.7%. This signals that there is an easy to overcome and exploit synergy between Syndra and Cassiopeia that allows them to perform worse together than without each other.
Cassiopeia has a greater difficulty than Syndra. That means you must be very careful when finding Cassiopeia comrades to play with, as they will need a greater level of skill to be able to cooperate well with you.
Playing on the same side, you should witness an overall large increase in your team’s capacity to deal magic damage. Combined, these two are able to dish out a surprising amount of magic type damage.
Although, by pairing Syndra and Cassiopeia together, you will not be granting your other teammates a lot of attack damage. Make sure to pick other champions on your team that offsets this relative gap in this pairing's kit.
Regardless of your Cassiopeia ally's ability, you need to focus on increasing your income, warding to avoid ambushes, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
If you would like to learn all of the intricacies of Syndra in order to work well with Cassiopeia during both the laning and mid / late game phases of League, you should keep reading to pick up some more lessons on this champion pairing. If you mind the build and stats displayed here, you will increase your win rate by a lot.
The best finished items to get in your Syndra and Cassiopeia synergy build include Shadowflame, Stormsurge, and Luden's Companion. When Syndra included at least these three great items in her build, she did significantly better when fighting alongside Cassiopeia than with many other common builds. In fact, Syndra had an average win rate of 44.7% when playing alongside Cassiopeia with this build.
To have the greatest chance of beating your oponents, you should equip the First Strike, Magical Footwear, Minion Dematerializer, Cosmic Insight, Manaflow Band, and Transcendence runes from the Inspiration and Sorcery rune sets. Of all the rune combinations players chose for Syndra and Cassiopeia pairings, this mix of runes resulted in the highest win rate. Notably, these runes gave a 44.7% winrate overall.
By default, tips, stats, and builds on how to pair Cassiopeia with Syndra are given for all ranked divisions. If you would like to scope the stats and builds to a distinct rank, you can use the selection menu at the top of this page.